1. We want to analyze a design that is without replications, i.e. n=1 ("S", not "G"). How do we have to change our assumptions?
2. We want to analyze a design that is incomplete, i.e. not all treatment combinations are used. How do we have to change our assumptions?
3. Why might we add a blocking factor or two to a complete factorial n=1 design?
4. What are the consequences?
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