Final Outline

Topics outline

General Linear Model (GLM)
 
Common to all
Matrix form of the model, meaning of the parts
Design (variables and coefficients) vs. noise
Assumptions
Underlying Normal distribution - what is normally distributed? Mean = ? Variance = ?
Estimation - what is estimated? Using what method?
General matrix solution for the normal equations. What are they?
Plots: visualize the data, assess normality, assess homoscedasticity

 
Regression
Models
Simple Linear Regression (SLR)
Multiple Regression
Designs with replicates
Pure error and Tests of Fit
SLR - Simple Linear Regression
Model
Parameters, parameter estimation formulas
Predicted Ys, residuals
Hypotheses
t-tests for β0, β1
Test of Regression
Pure error and Test of Fit
Coefficient of Determination
Multiple Regression
Various models
Tests of individual βs
Test of "Regression"
Pure error and Test of Fit
Coefficient of Determination

 
Analysis of Variance (ANOVA)
Designs
Completely randomized single-factor design (CR-SF)
Randomized complete-block single-factor design (RCB-SF) (Example was one blocking factor, one treatment factor)
Randomized block incomplete factorial (RB-IF) (Example was the Latin Square design with 2 blocking factors, one treatment factor.)
CR-CF 2-way and 3-way designs
Randomized complete block design (one blocking factor, two treatment factors)
2k complete and n > 1 (replicated design)
2k complete and n = 1 (non-replicated design)
2k incomplete, n > 1 or n = 1
ANOVA topics:
The statistical model (GLM)
Means coding, effects coding
Estimation, what is estimated
Purposes of DOE
Elimination of systematic bias
Increasing statistical precision
Hypotheses
Hypotheses in means coding: matrices/vectors and the Kronecker product, later the 2k trick
Hypotheses in effects coding: when are interactions assumed = 0?
Comparisons other than the major effects
Single-df contrasts/comparisons
Multiple comparisons
Experimentwise error and methods to deal with it
Bonferroni
Tukey
Dunnett
Calculating SSsand dfs, then MS and F
Why the F test, which compares variances, tests means/effects
"G" (replicated) vs. "S" (non-replicated) designs, and the consequences
"G" designs
Residual = score - group mean
SSE = sum of squared residuals (or other SS formula)
"S" designs
Special formula for residuals, or no formula
Assume certain interactions = 0
"Pool" SS and df; then SSE = SST - SSall included effects
Incomplete 2k designs
Patterns of confounding
Orthogonal contrasts
Completely confounded contrasts
Partially confounded contrasts
Reducing the number of observations without reducing the number of factors, in a principled way that produces favorable patterns of confounding. Use of the generating function to choose cells to eliminate and to predict confounds.
Introducing blocking factors without raising the number of observations, in a principled way that produces favorable patterns of confounding. Use of the generating function to predict confounds and to form the blocks.
Useful plots
Plotting the means of groups
Sorted residuals vs. Normal quantiles: assess normality
Residuals vs. group membership or group means: assess equality of variance
In 2k designs, Effect size vs. Normal quantiles: determine which effects are likely = 0, with their variance reflecting only noise, and so are candidates for pooling into the error term

 
Statistical control charts
X-bar chart
R chart



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